Expression and function of a CP 339 , 818 – sensitive K + current in a 1 subpopulation of putative nociceptive neurons from adult mouse 2 trigeminal ganglia 3 4 5
نویسندگان
چکیده
Expression and function of a CP339,818–sensitive K current in a 1 subpopulation of putative nociceptive neurons from adult mouse 2 trigeminal ganglia 3 4 5 Luigi Sforna, Maria Cristina D’Adamo, Ilenio Servettini, Luca Guglielmi, Mauro Pessia, Fabio 6 Franciolini and Lugi Catacuzzeno 7 8 9 Dipartimento di Chimica, Biologia e Biotecnologie, Universita’ di Perugia, via Elce di Sotto 8, Perugia, Italy 10 1 Dipartimento di Medicina Sperimentale, Facolta’ di Medicina e Chirurgia, , Universita’ di Perugia 11 12 13 14 15 16 A CP–sensitive K current in trigeminal ganglion neurons 17 18 19 20 21 22 23 * Corresponding authors: 24 25 Dr Luigi Catacuzzeno 26 Dipartimento di Chimica, Biologia e Biotecnologie 27 Universita’ di Perugia 28 via Elce di Sotto 8, Perugia, Italy 29 Tel: +39.75.585-5755 30 email: [email protected] 31 32
منابع مشابه
Expression and function of a CP339,818-sensitive K⁺ current in a subpopulation of putative nociceptive neurons from adult mouse trigeminal ganglia.
Trigeminal ganglion (TG) neurons are functionally and morphologically heterogeneous, and the molecular basis of this heterogeneity is still not fully understood. Here we describe experiments showing that a subpopulation of neurons expresses a delayed-rectifying K(+) current (IDRK) with a characteristically high (nanomolar) sensitivity to the dihydroquinoline CP339,818 (CP). Although submicromol...
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